Open AccessCurrent perspectives in the treatment of resistant schizophrenia
Author(s) -
Solanki Rk,
P. P. Singh,
Deepti Munshi
Publication year - 2009
Publication title -
indian journal of psychiatry/indian journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.485
H-Index - 34
eISSN - 1998-3794
pISSN - 0019-5545
DOI - 10.4103/0019-5545.58289
Subject(s) - risperidone , schizophrenia (object oriented programming) , clozapine , olanzapine , psychiatry , medicine , adjunctive treatment , intensive care medicine , psychology
This article summarizes the current knowledge base on the diagnosis and management of treatment resistant schizophrenia. While the prevalence of treatment resistant schizophrenia is definition dependent, estimates have ranged from 30% to up to 60%. This article first looks into the various diagnostic criteria of treatment resistant schizophrenia. Then the literature is reviewed about the pharmacotherapeutics of its management. Clozapine emerges to be the gold standard. In addition risperidone and high dose olanzapine also emerge as clinically useful options. Other emerging adjunctive treatment options are equally addressed.