Open AccessSyndrome of inappropriate ADH secretion (SIADH) associated with citalopram use
Author(s) -
Vivek Kirpekar,
Prashant Joshi
Publication year - 2005
Publication title -
indian journal of psychiatry/indian journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.485
H-Index - 34
eISSN - 1998-3794
pISSN - 0019-5545
DOI - 10.4103/0019-5545.55960
Subject(s) - citalopram , medicine , antidiuretic , hyponatremia , hormone , intensive care medicine , serotonin , receptor
Selective serotonin reuptake inhibitors (SSRIs) can cause the syndrome of inappropriate antidiuretic hormone secretion (SIADH). SIADH is associated with hyponatraemia without oedema. We report the case of a patient who developed acute-onset hyponatraemia that progressed rapidly to serious neurological dysfunction shortly after the introduction of citalopram. All SSRIs including citalopram should be used with care in the elderly. The water and electrolyte balance should be monitored carefully during SSRI therapy.