Open AccessSerotonin transporter gene polymorphism and treatment response to serotonin reuptake inhibitor (escitalopram) in depression: An open pilot study
Author(s) -
Mushtaq Ahmad Margoob,
Dhuha Mushtaq,
Imtiyaz Murtza,
Huda Mushtaq,
Arif Ali
Publication year - 2008
Publication title -
indian journal of psychiatry/indian journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.485
H-Index - 34
eISSN - 1998-3794
pISSN - 0019-5545
DOI - 10.4103/0019-5545.39759
Subject(s) - escitalopram , serotonin transporter , serotonin reuptake inhibitor , serotonin , citalopram , reuptake inhibitor , serotonin plasma membrane transport proteins , psychology , polymorphism (computer science) , medicine , pharmacology , genotype , psychiatry , gene , biology , antidepressant , genetics , receptor , anxiety
Blocking of the serotonin transporter is the main mechanism of action of SSRIs; therefore, the gene encoding this protein is a strong candidate for a possible genetic influence on the treatment response.