Open AccessCircadian clock gene aryl hydrocarbon receptor nuclear translocator-like polymorphisms are associated with seasonal affective disorder: An Indian family study
Author(s) -
Bhagya Rajendran,
V. N. Janakarajan V. N. Janakarajan
Publication year - 2016
Publication title -
indian journal of psychiatry/indian journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.485
H-Index - 34
eISSN - 1998-3794
pISSN - 0019-5545
DOI - 10.4103/0019-5545.174374
Subject(s) - aryl hydrocarbon receptor nuclear translocator , aryl hydrocarbon receptor , circadian rhythm , single nucleotide polymorphism , biology , genetics , family history , genotyping , allele , medicine , genotype , endocrinology , gene , transcription factor
Polymorphisms in aryl hydrocarbon receptor nuclear translocator-like (ARNTL) gene, the key component of circadian clock manifests circadian rhythm abnormalities. As seasonal affective disorder (SAD) is associated with disrupted circadian rhythms, the main objective of this study was to screen an Indian family with SAD for ARNTL gene polymorphisms.