Open AccessQT prolongation and torsades de pointes with psychotropic agents
Author(s) -
Nagaraj Desai,
Chilkunda Raviprakash Venkatesh,
S. Sunil Kumar
Publication year - 2015
Publication title -
indian journal of psychiatry/indian journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.485
H-Index - 34
eISSN - 1998-3794
pISSN - 0019-5545
DOI - 10.4103/0019-5545.166619
Subject(s) - torsades de pointes , qt interval , prolongation , medicine , long qt syndrome , cardiology
The unexpected and catastrophic cardiovascular effects of psychotropic drugs are well described albeit uncommon. The list of drugs which have been associated with prolonging QT interval and hence potentially causing Torsades de pointes is exhaustive. The insight into the plausible mechanisms are largely unclear. However, the practical implications of anticipating and recognizing QT prolongation cannot be overemphasized.