Open AccessEvaluation of hydroxyapatite and beta-tricalcium phosphate mixed with bone marrow aspirate as a bone graft substitute for posterolateral spinal fusion
Author(s) -
Shonak Bansal,
Vijendra Chauhan,
Sansar Sharma,
Rajesh Maheshwari,
Anil Juyal,
Shailendra Raghuvanshi
Publication year - 2009
Publication title -
indian journal of orthopaedics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.434
H-Index - 33
eISSN - 1998-3727
pISSN - 0019-5413
DOI - 10.4103/0019-5413.49387
Subject(s) - medicine , iliac crest , bone marrow aspirate , spinal fusion , cancellous bone , surgery , lumbar , bone marrow , pseudarthrosis , pathology
Autologous cancellous bone is the most effective biological graft material. However, harvest of autologous bone is associated with significant morbidity. Since porous hydroxyapatite and beta-tricalcium phosphate are biodegradable materials and can be replaced by bone tissue, but it lacks osteogenic property. We conducted a study to assess their use as a scaffold and combine them with bone marrow aspirate for bone regeneration using its osteogenic property for posterolateral spinal fusion on one side and autologous bone graft on the other side and compare them radiologically in terms of graft incorporation and fusion.