Open AccessRetrospective cohort study comparing the efficacy of prednisolone and deflazacort in children with muscular dystrophy
Author(s) -
Harish Petnikota,
Vrisha Madhuri,
Sangeet Gangadharan,
Indira Agarwal,
Belavendra Antonisamy
Publication year - 2016
Publication title -
indian journal of orthopaedics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.434
H-Index - 33
eISSN - 1998-3727
pISSN - 0019-5413
DOI - 10.4103/0019-5413.189609
Subject(s) - deflazacort , medicine , muscular dystrophy , prednisolone , duchenne muscular dystrophy , pediatrics , muscle biopsy , wasting , surgery , biopsy
Muscular dystrophies are inherited myogenic disorders characterized by progressive muscle wasting and weakness of variable distribution and severity. They are a heterogeneous group characterized by variable degree of skeletal and cardiac muscle involvement. The most common and the most severe form of muscular dystrophy is DMD. Currently, there is no curative treatment for muscular dystrophies. Several drugs have been studied to retard the progression of the muscle weakness. There is much controversy about steroid usage in muscular dystrophy with respect to regimen, adverse effects, and whether long term benefits outweigh side effects. This study is to assess steroid efficacy in children with muscular dystrophy.