Open AccessNight work and inflammatory markers
Author(s) -
Sadeghniiat Haghighi Khosro,
Safaiyan Alireza,
Omid Aminian,
Sharifi Forough
Publication year - 2011
Publication title -
the indian journal of occupational and environmental medicine/the indian journal of occupational and environmental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.375
H-Index - 26
eISSN - 1998-3670
pISSN - 0973-2284
DOI - 10.4103/0019-5278.82996
Subject(s) - shift work , medicine , sleep deprivation , monocyte , interleukin 6 , inclusion and exclusion criteria , inflammation , circadian rhythm , psychiatry , pathology , alternative medicine
Various adverse health effects associated with shift work have been documented in the medical literature. These include increased risk of cardiovascular disorders, cerebrovascular disorders, and mortality. Sleep deprivation has been shown to be associated with an elevation in inflammatory makers such as interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-α), and C-reactive protein (CRP). It is hypothesized that the increased risk of many disorders associated with shift work may be due to inflammatory processes resulting from sleep deprivation. The purpose of this study was to investigate the relationship between night work and inflammatory markers.