Open AccessOccupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later
Author(s) -
Ravi Kumar Y,
Manthappa,
Praveen Kumar,
Manish Prasad,
A Radhika,
Edara Ac
Publication year - 2014
Publication title -
the indian journal of occupational and environmental medicine/the indian journal of occupational and environmental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.375
H-Index - 26
eISSN - 1998-3670
pISSN - 0973-2284
DOI - 10.4103/0019-5278.146899
Subject(s) - methemoglobinemia , antidote , methylene blue , methemoglobin , medicine , inhalation , anemia , aniline , anesthesia , hemoglobin , chemistry , toxicity , organic chemistry , photocatalysis , catalysis
Methylene blue is utilized as the main treatment of methemoglobinemia. Here we report two cases, in which patient suffered from aniline-induced methemoglobinemia with initial good response but later developed haemolytic anemia due to methylene blue therapy. He was treated with hydration, high flow oxygen and steroid therapy. Caution should be exercised while using methylene blue as antidote of acute methemoglobinemia as both methemoglobinemia and its antidote methylene blue can itself precipitate fatal haemolytic anemia.