Open AccessResponse of T-cell subpopulations to superantigen and recall antigen stimulation in systemic sclerosis
Author(s) -
Sajad Ahmad Dar,
S N Bhattacharya,
Shukla Das,
V G Ramachandran,
Basu Dev Banerjee,
Prateek Arora
Publication year - 2012
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.96187
Subject(s) - superantigen , antigen , immunology , t cell , medicine , stimulation , cd8 , b cell , immune system , antibody
There is great disagreement regarding which effector T-cells are responsible for the pathogenesis of systemic sclerosis. Further, the possible role of superantigens in modulating the T-cell phenotype responsible for the immunopathogenesis of this disease and the response of these patients to common recall antigens have not been adequately determined.