Allogenic hematopoietic stem cell transplantation in pemphigus vulgaris: A single-center experience | Zendy

ArunaV Vanikar | Zendy; HargovindL Trivedi | Zendy; RashmiD Patel | Zendy; KamalV Kanodia | Zendy; Pranjal Modi | Zendy; VeenaR Shah | Zendy

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Allogenic hematopoietic stem cell transplantation in pemphigus vulgaris: A single-center experience

Author(s) -

ArunaV Vanikar,

HargovindL Trivedi,

RashmiD Patel,

KamalV Kanodia,

Pranjal Modi,

VeenaR Shah

Publication year - 2012

Publication title -

indian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 36

eISSN - 1998-3611

pISSN - 0019-5154

DOI - 10.4103/0019-5154.92667

Subject(s) - medicine , pemphigus vulgaris , hematopoietic stem cell transplantation , stem cell , bone marrow , cd34 , graft versus host disease , single center , group b , transplantation , autoantibody , gastroenterology , immunology , antibody , biology , genetics

Pemphigus vulgaris (PV), an autoimmune disorder characterized by blistering skin/mucus membrane lesions, is mediated by desmoglein-3 autoantibodies. We carried out a prospective clinical trial of hematopoietic stem cell transplantation (HSCT) in thymus, bone marrow (BM) and periphery to reconstitute central and peripheral arms of self-tolerance.

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