Open AccessA study of pathogenesis of Acanthosis nigricans and its clinical implications
Author(s) -
Neerja Puri
Publication year - 2011
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.91828
Subject(s) - acanthosis nigricans , medicine , acanthosis , pathogenesis , intertriginous , malignancy , testosterone (patch) , dermatology , papillomatosis , physical examination , pathology , hyperkeratosis , gastroenterology , obesity , disease , insulin resistance
Acanthosis nigricans (AN) is a dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck. Common in some populations, its prevalence depends on race. Clinicians should recognize AN; it heralds disorders ranging from endocrinologic disturbances to malignancy. In this review, we discuss the pathogenesis of AN and its clinical implications and management.