Open AccessCytophagic histiocytic panniculitis: Report of two cases
Author(s) -
Jayasree Manoj,
Feroze Kaliyadan,
Manoj Unni,
AD Dharmaratnam
Publication year - 2011
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.82487
Subject(s) - medicine , pancytopenia , panniculitis , organomegaly , histiocyte , malaise , pathology , dermatology , histiocytosis , disease , bone marrow , surgery
Cytophagic histiocytic panniculitis (CHP) was first described in 1980 by Winkelmann as a chronic histiocytic disease of the subcutaneous adipose tissue, which is characterized clinically by tender erythematous nodules, recurrent high fever, malaise, jaundice, organomegaly, serosal effusions, pancytopenia, hepatic dysfunction, and coagulatory abnormalities. CHP may occur either isolated or as part of cutaneous manifestations of hemophagocytic syndrome. Here, we report two different presentations of CHP.