Open AccessURIC acid : A new antioxidant in patients with pemphigus vulgaris
Author(s) -
Maryam Yousefi,
Hamzeh Rahimi,
Behrooz Barikbin,
Parviz Toossi,
Sara Lotfi,
Mehdi Hedayati,
Shima Younespour
Publication year - 2011
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.82480
Subject(s) - medicine , uric acid , pemphigus vulgaris , gastroenterology , antioxidant , oxidative stress , lipid peroxidation , psoriasis , venous blood , immunology , biochemistry , chemistry
Increased reactive oxygen species (ROS) and lipid peroxidation are seen in many dermatologic disorders, for example, atopic dermatitis, psoriasis, vitiligo, acne vulgaris, pemphigus vulgaris (PV), lichen planus, and alopecia areata. ROS has an important role in the inflammation process. In PV, increased production of ROS leads to decline of antioxidants in plasma and red blood cells which results in oxidative stress. We aimed to evaluate the level of these antioxidants in PV patients and compare it to the controls.