Open AccessAssessing the autoantibody levels in relation to disease severity and therapy response in pemphigus patients
Author(s) -
Deniz Aksu,
Yavuz Peksarı,
İbrahim Etem Arıca,
Erbak Gürgey
Publication year - 2010
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.74536
Subject(s) - medicine , autoantibody , pemphigus , pemphigus vulgaris , antibody , disease , titer , immunology , antibody titer , desmoglein , lesion , paraneoplastic pemphigus , pathology
In pemphigus, autoantibodies are directed against adhesion molecules, which make the junctions between keratinocytes, and thus determining their level can reflect the disease activity.