Study of reservoir effect of clobetasol propionate cream in an experimental animal model using histamine-induced wheal suppression test
Author(s) -
Afroz Abidi,
Farida Ahmad,
SatyendraK Singh,
Anil Kumar
Publication year - 2010
Publication title -
indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.74531
Subject(s) - clobetasol propionate , medicine , histamine , topical steroid , corticosteroid , stratum corneum , pharmacology , dermatology , pathology
Topical corticosteroids used in various dermatological diseases several times a day led to an increase risk of side effects. By demonstrating a significant reservoir of corticosteroids in the stratum corneum, one can maximize their efficacy and safety as therapeutic agents.
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