Assessment of serum homocysteine, endothelin-1, and nitric oxide levels in behçet′s disease | Zendy

AbeerA Hodeib | Zendy; TarekA Elsharawy | Zendy; HishamA Fawzi | Zendy

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Assessment of serum homocysteine, endothelin-1, and nitric oxide levels in behçet′s disease

Author(s) -

AbeerA Hodeib,

TarekA Elsharawy,

HishamA Fawzi

Publication year - 2010

Publication title -

indian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 36

eISSN - 1998-3611

pISSN - 0019-5154

DOI - 10.4103/0019-5154.70667

Subject(s) - hyperhomocysteinemia , homocysteine , medicine , nitric oxide , endothelial dysfunction , gastroenterology , platelet activation , behcet's disease , endothelin receptor , nitrite , endocrinology , immunology , platelet , disease , chemistry , receptor , organic chemistry , nitrate

Some prominent features of Behçet's disease (BD) are arterial and venous thromboses as a result of endothelial dysfunction. Hyperhomocysteinemia is responsible for vascular endothelial injury due to an increased frequency of thrombogenesis. Endothelin-1 (ET-1) is a vasoconstrictor whereas nitric oxide (NO) is an endothelial vasorelaxing peptide that is responsible for the inhibition of platelet adhesion.

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