Open AccessHyper IgE syndrome with umbilical hernia
Author(s) -
NC Hiremath,
NT Madan Mohan,
CR Srinivas,
Prabhakar Sangolli,
K Srinivas,
Neelakanta Pillai P Soumya
Publication year - 2009
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.57619
Subject(s) - medicine , umbilical hernia , immunoglobulin e , immunology , inguinal hernia , atopic dermatitis , dermatology , hernia , antibody , surgery
Hyper IgE Syndrome (HIES) is a rare multi system genetic immunodeficiency disorder, with immunological and non-immunological features. Immunolgical features are 1) Recurrent cutaneous abscesses, 2) Atopic dermatitis like lesions, 3) Sino pulmonary infections, 4) Elevated serum IgE levels and 5) Abnormal neutrophil chemotaxis. Non immunological features include cranio facial and skeletal abnormalities. We are reporting a girl with classical features of HIES with umbilical hernia with her younger brother suffering from right sided inguinal hernia, as both herniae are hitherto unreported in patients with HIES.