Open AccessDiffuse plane xanthomatosis in a patient withBudd-Chiari syndromeand monoclonal gammopathy
Author(s) -
Mukadder Koçak,
Hatice Keleş,
Fahri Yakaryılmaz,
Önder Bozdoğan,
Sefa Güliter
Publication year - 2009
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.57616
Subject(s) - medicine , monoclonal gammopathy , pathology , xanthoma , buttocks , anatomy , monoclonal , monoclonal antibody , antibody , immunology
Diffuse plane xanthomas are characterized by the presence of yellowish plaques on the eyelids, neck, upper trunk, buttocks, and flexural folds. Histology shows foamy histiocytes in the dermis. Approximately half of the cases are associated with lymphoproliferative disorders. Budd-Chiari syndrome is an uncommon condition induced by thrombotic or nonthrombotic obstruction of hepatic venous outflow. We present a case of diffuse plane xanthoma in a 62-year-old man who developed normolipemic plane xanthomas coinciding with Budd-Chiari syndrome and monoclonal gammopathy. We review the English-language literature regarding the rare association of xanthomas and Budd-Chiari syndrome.