Open AccessGeneralized morphea following radiotherapy for an intracranial tumor
Author(s) -
Shrenik Balegar,
Dharmendra Kumar Mishra,
Sagarika Chatterjee,
Shweta Kumari,
Anup Kumar Tiwary
Publication year - 2016
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.190132
Subject(s) - morphea , medicine , radiation therapy , dermatology , etiology , localized scleroderma , incidence (geometry) , scleroderma (fungus) , radiology , trunk , cyclophosphamide , surgery , pathology , chemotherapy , lichen sclerosus , ecology , physics , biology , optics , inoculation
Morphea is a localized scleroderma variety which can be circumscribed or generalized and is characterized by sclerotic plaques developing on trunk and limbs. Surgery and radiation have been implicated as etiological factors for the development of morphea. Majority of the radiation-induced morphea cases have occurred in patients with breast cancer. The affected areas have been generally restricted to the area of radiation and nearby surrounding area in most of the reported cases. We hereby report a case of a 27-year-old male who developed radiation-induced progressive generalized morphea after getting radiotherapy for an intracranial tumor. His condition improved after dexamethasone-cyclophosphamide pulse therapy. With increased incidence of cancer worldwide and radiotherapy as a modality of treatment, it is imperative to follow the patient and look for the development of morphea which itself is a debilitating disease