Open AccessCD8-positive mycosis fungoides masquerading as pyoderma gangrenosum
Author(s) -
Manika Saha,
B.D. Jain,
S. Chattopadhyay,
Indrashis Podder
Publication year - 2016
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.190126
Subject(s) - mycosis fungoides , pyoderma gangrenosum , medicine , cd5 , presentation (obstetrics) , dermatology , histopathology , pathology , lymphoma , dermatopathology , immunohistochemistry , cutaneous t cell lymphoma , peripheral t cell lymphoma , t cell , immunology , surgery , immune system , disease
Mycosis fungoides (MF), a primary cutaneous T-cell lymphoma, accounts for <1% of non-Hodgkin lymphomas. The diagnosis of classic MF is based on a constellation of typical clinical presentation, histopathology, immunohistochemistry, and T-cell monoclonality detected by molecular studies. Rarely, atypical clinical presentation may occur. The typical immunohistochemical phenotype is, CD2 +ve, CD3 +ve, CD5 +ve, CD4 +ve, and CD8 − ve. Here, we report a rare case of CD8 +ve MF in a 43-year-male patient who was clinically diagnosed as pyoderma gangrenosum initially. The atypical presentation and rarity of such case have prompted this report