Significance of anti-cyclic citrullinated peptide autoantibodies in immune-mediated inflammatory skin disorders with and without arthritis | Zendy

Bineeta Kashyap | Zendy; Chander Grover | Zendy; Deepashree Daulatabad | Zendy; Amit Dhawan | Zendy; IqbalR Kaur | Zendy

Open Access

Significance of anti-cyclic citrullinated peptide autoantibodies in immune-mediated inflammatory skin disorders with and without arthritis

Author(s) -

Bineeta Kashyap,

Chander Grover,

Deepashree Daulatabad,

Amit Dhawan,

IqbalR Kaur

Publication year - 2016

Publication title -

indian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 36

eISSN - 1998-3611

pISSN - 0019-5154

DOI - 10.4103/0019-5154.190122

Subject(s) - medicine , autoantibody , immune system , immunology , arthritis , auto immune , inflammatory arthritis , rheumatoid arthritis , antibody

Anti-cyclic citrullinated peptides (CCPs) are autoantibodies directed against citrullinated peptides. Rheumatoid factor (RF), an antibody against the Fc portion of IgG, is known to form immune complexes and contribute to the etiopathogenesis of various skin disorders. C-reactive protein (CRP), an acute-phase protein, increases following secretion of interleukin-6 from macrophages and T cells. Anti-CCP, RF, and CRP are well-established immune-markers, their diagnostic potential in immune-mediated skin disorders remains less widely studied.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research