Open AccessNodulocystic basal cell carcinoma arising directly from a seborrheic keratosis: A rare case report
Author(s) -
Kana Shibao,
Naoko Okiyama,
Ryota Tanaka,
Hitoshi Maruyama,
Yasuhiro Fujisawa,
Manabu Fujimoto
Publication year - 2016
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.185720
Subject(s) - seborrheic keratosis , medicine , basal cell carcinoma , dermatology , keratosis , pathology , malignant transformation , basal cell
Seborrheic keratoses (SKs) are common epidermal tumors composed of benign keratinocytes. Malignant skin tumors including basal cell carcinoma (BCC) rarely arise within SKs. We report a rare case of an 82-year-old man with nodulocystic BCC that appeared at the center of a scaly hyperpigmented SK that had been presented for more than 10 years. It was histologically confirmed that CK19-positive BCC arose directly from the wall of the pseudohorn cyst, a part of the SK. Nodular and/or cystic BCC also rarely arise within SKs while the most common histologic type of BCC within SKs is the superficial type. Careful observation of SKs is important even though it is rarely a background condition for malignant transformation.