Open AccessChromoblastomycosis associated with bone and central nervous involvement system in an immunocompetent child caused by exophiala spinifera
Author(s) -
Sahana M Srinivas,
Vykuntaraju K Gowda,
S Mahantesh,
Rajeshwari Mannapur,
Sanjay K Shivappa
Publication year - 2016
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.182425
Subject(s) - chromoblastomycosis , itraconazole , medicine , voriconazole , osteomyelitis , dermatology , pathology , surgery , antifungal
Chromoblastomycosis is a chronic granulomatous infection of the skin and subcutaneous tissue caused by specific group of dematiaceous fungi. The infection results from traumatic injury and is seen more commonly on feet and lower legs. It is rarely seen in children and metastatic spread to other systems is exceptionally rare. We report a 12-year-old immunocompetent male child diagnosed with chromoblastomycosis on the lower leg, who in a span of few months developed osteomyelitis and left hemiparesis. Fungal culture showed growth of Exophiala spinifera. Child showed good improvement with voriconazole and itraconazole after 1 year of treatment. Skin lesions healed with minimal scarring and his power improved.