Open AccessPlasma cell neoplasm manifesting initially as a sub-cutaneous supra-orbital swelling
Author(s) -
Riddhi Jaiswal,
Garima Agarwal,
Sudhir Singh
Publication year - 2016
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.174093
Subject(s) - medicine , multiple myeloma , prednisone , asymptomatic , monoclonal gammopathy of undetermined significance , bortezomib , plasma cell myeloma , plasma cell neoplasm , plasma cell leukemia , neoplasm , monoclonal , pathology , dermatology , surgery , plasmacytoma , monoclonal antibody , antibody , immunology
Multiple myeloma is a plasma cell neoplasm seen usually in patients over 50 years of age. Some cases may be asymptomatic initially and are detected during a routine test like complete blood count. They only require a close follow-up and monitoring. However, around 1% of these monoclonal gammopathy of undetermined significance progress to multiple myeloma every year and then they need to be taken care of by chemotherapy, targeted therapy, bisphosphonates and 6 monthly urine and bone examinations. Here, we present a case of 35-year-old female with an initial symptom of a vague backache along with a left subcutaneous supra-orbital swelling which was diagnosed as multiple myeloma by aspiration cytology and confirmed by ancillary tests. She has since been on treatment with bortezomib and prednisone and is responding well