Open AccessRecurrent diffuse neurofibroma of nose associated with neurofibromatosis type 1: A rare case report with review of literature
Author(s) -
Vimal Chander,
Surya Rao Rao Venkata Mahipathy,
Ganthimathy Sekhar,
A. Raja,
M Sridevi
Publication year - 2015
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.169128
Subject(s) - medicine , neurofibroma , neurofibromatosis , ectasia , nose , head and neck , pathology , dorsum , neurofibromatosis type i , café au lait spot , dermatology , anatomy , surgery
Diffuse neurofibroma is an unusual variant of neurofibroma with the head and neck being the common sites of involvement. It is benign in nature and spreads superficially and has many ectatic blood vessels. Histologically it is similar to conventional neurofibromas except for a few peculiar distinguishing features. We report a case of a 14-year-old boy who presented with a diffuse recurrent painless swelling over the dorsum of the nose with the clinical stigmata of neurofibromatosis. Microscopy revealed a diagnosis of diffuse neurofibroma with a few foci showing differentiation towards Meissner's type of tactile corpuscles. It is important to recognize this entity as it has a tendency to recur, yet hardly ever become malignant and is almost always associated with neurofibromatosis type 1.