Alitretinoin in dermatology-An update | Zendy

AdityaKumar Bubna | Zendy

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Alitretinoin in dermatology-An update

Author(s) -

AdityaKumar Bubna

Publication year - 2015

Publication title -

indian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 36

eISSN - 1998-3611

pISSN - 0019-5154

DOI - 10.4103/0019-5154.164426

Subject(s) - medicine , dermatology , retinoid , retinoic acid , systemic therapy , biochemistry , chemistry , cancer , breast cancer , gene

Alitretinoin is a pan retinoic acid agonist. It was initially used as 0.1% gel in the management of localized Kaposi′s sarcoma. At present, the use of systemic alitretinoin has proved extremely efficacious in the management of recalcitrant chronic hand eczema. Furthermore, there have been other retinoid responsive dermatosis that have demonstrated remission post usage of systemic alitretinoin. With a better toxicity profile, compared to the other systemic retinoids, alitretinoin could be considered a valuable treatment option in the near future for the treatment of these dermatologic disorders

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