Open AccessD-penicillamine induced degenerative dermopathy
Author(s) -
Sujay Khandpur,
Neha Jain,
Shweta Singla,
Priti Chatterjee,
Madhuri Behari
Publication year - 2015
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.160498
Subject(s) - medicine , penicillamine , cutis laxa , elastin , dermatology , cutis , pathology
D-penicillamine interferes with elastin and collagen metabolism and produces several cutaneous and multi-systemic side-effects. We present two cases of Wilson's disease who on long-term penicillamine therapy developed drug-induced degenerative dermopathy manifesting as skin fragility over pressure sites and cutis laxa-like changes.