Open AccessMultiple synchronous verrucous carcinomas of the scalp in the background of generalized verruca vulgaris
Author(s) -
Arvind Krishnamurthy,
Vijayalakshmi Ramshankar,
Soundara Viveka Thangaraj,
Urmila Majhi
Publication year - 2015
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.152524
Subject(s) - verruca vulgaris , scalp , medicine , verrucous carcinoma , human papillomavirus , immunohistochemistry , dermatology , basal cell , pathology , presentation (obstetrics) , radiology
Verrucous carcinoma (VC) is a clinicopathologic entity which is defined as a locally aggressive, clinically exophytic, slow-growing, well-differentiated, squamous cell carcinoma with negligible metastatic potential. The cutaneous form of VC is typically known to arise from the palmoplantar and the genitocrural areas. Involvement of the scalp is extremely rare. Multiple synchronous involvement of the scalp by VC along with associated generalized verruca vulgaris has possibly never been reported before. We present this unique report of VC in a 38-year-old male patient with emphasis on its atypical clinical presentation and the resultant challenges in management. Interestingly, the tumor cells of our patient were confirmed to be positive for human papillomavirus infection by polymerase chain reaction and by p16 immunohistochemistry.