Male genital lichen sclerosus | Zendy

Clareann H. Bunker | Zendy; TangNgee Shim | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Male genital lichen sclerosus

Author(s) -

Clareann H. Bunker,

TangNgee Shim

Publication year - 2015

Publication title -

indian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 36

eISSN - 1998-3611

pISSN - 0019-5154

DOI - 10.4103/0019-5154.152501

Subject(s) - medicine , lichen sclerosus , foreskin , dermatology , meatal stenosis , penis , etiology , complication , sex organ , surgery , pathology , urethra , genetics , urethroplasty , biology , cell culture

Male genital lichen sclerosus (MGLSc) is a chronic inflammatory skin disease responsible for male sexual dyspareunia and urological morbidity. An afeared complication is squamous cell carcinoma (SCC) of the penis. The precise etiopathogenesis of MGLSc remains controversial although genetic, autoimmune and infective (such as human papillomavirus (HPV) hepatitis C (HCV), Epstein-Barr virus (EBV) and Borrelia) factors have been implicated: Consideration of all the evidence suggests that chronic exposure of susceptible epithelium to urinary occlusion by the foreskin seems the most likely pathomechanism. The mainstay of treatment is topical ultrapotent corticosteroid therapy. Surgery is indicated for cases unresponsive to topical corticosteroid therapy, phimosis, meatal stenosis, urethral stricture, carcinoma in situ (CIS) and squamous cell carcinoma.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research