Bullous lesions, sweat gland necrosis and rhabdomyolysis in alcoholic coma | Zendy

Neelakandhan Asokan | Zendy; VayappurathGangadharan Binesh | Zendy; AndrewsMekkattukunnel Andrews | Zendy; PattomthadathilSankaran Jayalakshmi | Zendy

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Bullous lesions, sweat gland necrosis and rhabdomyolysis in alcoholic coma

Author(s) -

Neelakandhan Asokan,

VayappurathGangadharan Binesh,

AndrewsMekkattukunnel Andrews,

PattomthadathilSankaran Jayalakshmi

Publication year - 2014

Publication title -

indian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 36

eISSN - 1998-3611

pISSN - 0019-5154

DOI - 10.4103/0019-5154.143576

Subject(s) - medicine , spongiosis , rhabdomyolysis , sweat gland , coma (optics) , necrosis , pathology , acute tubular necrosis , sweat , dermatology , surgery , kidney , physics , optics

A 42-year-old male developed hemorrhagic bullae and erosions while in alcohol induced coma. The lesions were limited to areas of the body in prolonged contact with the ground in the comatose state. He developed rhabdomyolysis, progressing to acute renal failure (ARF). Histopathological examination of the skin showed spongiosis, intraepidermal vesicles, and necrosis of eccrine sweat glands with denudation of secretory epithelial lining cells. With supportive treatment and hemodialysis, the patient recovered in 3 weeks time. This is the first reported case of bullous lesions and sweat gland necrosis occurring in alcohol-induced coma complicated by rhabdomyolysis and ARF

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