Open AccessBullous lesions, sweat gland necrosis and rhabdomyolysis in alcoholic coma
Author(s) -
Neelakandhan Asokan,
VG Binesh,
Andrews Mekkattukunnel Andrews,
Pattomthadathil Sankaran Jayalakshmi
Publication year - 2014
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.143576
Subject(s) - medicine , spongiosis , rhabdomyolysis , sweat gland , coma (optics) , necrosis , pathology , acute tubular necrosis , sweat , dermatology , surgery , kidney , physics , optics
A 42-year-old male developed hemorrhagic bullae and erosions while in alcohol induced coma. The lesions were limited to areas of the body in prolonged contact with the ground in the comatose state. He developed rhabdomyolysis, progressing to acute renal failure (ARF). Histopathological examination of the skin showed spongiosis, intraepidermal vesicles, and necrosis of eccrine sweat glands with denudation of secretory epithelial lining cells. With supportive treatment and hemodialysis, the patient recovered in 3 weeks time. This is the first reported case of bullous lesions and sweat gland necrosis occurring in alcohol-induced coma complicated by rhabdomyolysis and ARF