Open AccessCaveolin-1 expression in different types of psoriatic lesions: Analysis of 66 cases
Author(s) -
Feng Zhang,
Heyu Li,
Yifeng Zhou,
Yue Gu,
Lifeng Wang
Publication year - 2014
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.131374
Subject(s) - psoriasis , immunohistochemistry , medicine , caveolin 1 , immunostaining , pathology , pustular psoriasis , dermatology
Caveolin-1 is a key structural and functional protein. Caveolin-1 is known to modulate multiple signal-transducing pathways involved in cell differentiation and proliferation. Psoriasis is viewed as a multifactorial pathology characterized by keratinocyte hyperproliferation and abnormal cell maturation.