Open AccessSquamous cell carcinoma in a patient with vitiligo of photo-covered skin
Author(s) -
Asok Gangopadhyay,
Jayanta Kumar Das,
Amit Kumar Agarwal
Publication year - 2014
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.127685
Subject(s) - vitiligo , medicine , dermatology , psoralen , basal cell , skin cancer , ultraviolet light , puva therapy , ultraviolet a , pathology , psoriasis , cancer , dna , chemistry , genetics , photochemistry , biology
Ultraviolet radiation is an important risk factor for the development of skin cancers. Melanin is known to protect the skin against harmful effects of ultraviolet radiation. Hence, vitiligo patients are at higher risk of developing such malignancies. But few reports of occurrence of skin cancers in vitiligo lesions suggest that their occurrence in vitiligo is rare. There are reports of development of Squamous cell carcinoma (SCC) in vitiligo lesions, following long-term Psoralen and Ultraviolet-A (PUVA) therapy. But there are no reports of occurrence of SCC in a vitiligo patch located in photo-covered area. We describe a patient with SCC in a vitiligo patch present in photo-covered skin.