Open AccessPolyamine metabolism changes in psoriasis
Author(s) -
Valentina Broshtilova,
Valentin Lozanov,
Ljubka Miteva
Publication year - 2013
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.113952
Subject(s) - spermine , putrescine , spermidine , psoriasis , polyamine , biochemistry , medicine , chemistry , endocrinology , cancer research , dermatology , enzyme
Polyamines - putrescine, spermidine and spermine are polycationic compounds ubiquitous for all living organisms. They are essential for the cell growth and differentiation, the control of cell cycle progress, apoptosis, and cancerogenesis. Accumulated scientific evidence suggests the central role of polyamines in the process of keratinocytic proliferation, differentiation, and regulation.