Kojic acid vis-a-vis its combinations with hydroquinone and betamethasone valerate in melasma: A randomized, single blind, comparative study of efficacy and safety | Zendy

KirtiS Deo | Zendy; KedarN Dash | Zendy; YugalK Sharma | Zendy; NehaC Virmani | Zendy; Chetan Oberai | Zendy

Open Access

Kojic acid vis-a-vis its combinations with hydroquinone and betamethasone valerate in melasma: A randomized, single blind, comparative study of efficacy and safety

Author(s) -

KirtiS Deo,

KedarN Dash,

YugalK Sharma,

NehaC Virmani,

Chetan Oberai

Publication year - 2013

Publication title -

indian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 36

eISSN - 1998-3611

pISSN - 0019-5154

DOI - 10.4103/0019-5154.113940

Subject(s) - melasma , kojic acid , medicine , hydroquinone , dermatology , single blind , pharmacology , randomized controlled trial , double blind , tyrosinase , alternative medicine , organic chemistry , chemistry , enzyme , pathology , placebo

Melasma is a relatively common, acquired symmetric hypermelanosis characterized by irregular light to gray-brown macules involving sun-exposed areas. Kojic acid, with its depigmenting potential due to tyrosinase inhibition and suppression of melanogenesis, has become a vital component of the dermatologists' armamentarium against melasma.

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