Open AccessMonilethrix: A rare hereditary condition
Author(s) -
Adaikalampillai Ganapathy Vikramkumar,
Sheela Kuruvila,
Satyaki Ganguly
Publication year - 2013
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.110869
Subject(s) - penetrance , medicine , dermatology , sibling , genetics , phenotype , biology , gene , psychology , developmental psychology
Monilethrix is a rare hereditary condition generally considered to be an autosomal-dominant disorder with variable penetrance. Here, we report a case of monilethrix in a 13-year-old boy with an affected sibling. A therapeutic trial with oral N-acetyl cysteine was attempted. There was slight improvement after 2 months of therapy. The hair density, however, did not show any further improvement subsequently. Monilethrix remains as a therapeutic challenge for dermatologists