Open AccessMalignant acrospiroma of chest and abdominal wall treated with chemotherapy
Author(s) -
Anis Bandyopadhyay,
Moumita Das,
Sukumar Jana,
Anuradha Das
Publication year - 2013
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.110849
Subject(s) - medicine , dissection (medical) , lymph , lymph node , chemotherapy , axilla , wide local excision , sweat gland , axillary lymph node dissection , radiation therapy , axillary lymph nodes , radiology , breast cancer , surgery , cancer , pathology , sweat , sentinel lymph node
Acrospiroma denotes a group of benign ductal tumours of the eccrine sweat glands that may or may not be connected to the skin. Although various eccrine sweat gland tumours including benign acrospiroma are widely reviewed, malignant acrospiroma is rarely reported. Malignant acrospiroma have the propensity to recur locally and metastasizes to regional lymph nodes. The primary treatment is wide local excision with or without lymph node dissection. Local radiation is added in the presence of high risk features to reduce the risk of recurrence. We describe a case of a malignant acrospiroma involving wide areas of chest and abdominal wall with metastases to bilateral axillary lymph nodes in a 47 year old man showing minimal clinical response to combination chemotherapy and paclitaxel