Open AccessGeneralized granuloma annulare treated with monthly rifampicin, ofloxacin, and minocycline combination therapy
Author(s) -
Shilpa Garg,
Sukriti Baveja
Publication year - 2013
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.110828
Subject(s) - granuloma annulare , minocycline , medicine , rifampicin , ofloxacin , dermatology , leprosy , dermis , combination therapy , pathology , antibiotics , tuberculosis , microbiology and biotechnology , ciprofloxacin , biology
Granuloma annulare (GA) is a disease characterized by granulomatous inflammation of the dermis. A variant form of the disease, generalized granuloma annulare (GGA), can be observed in 15% of affected patients. Localized GA is likely to resolve spontaneously within months or a few years, whereas GGA can persist for decades. There are various therapies for treating GGA. Monthly combination therapy of rifampicin 600 mg, ofloxacin 400 mg, and minocycline 100 mg (ROM) is used for treating paucibacillary leprosy which shares both clinical and histopathologic similarities with GA. Therefore, we decided to evaluate the possible efficacy of monthly ROM in a patient with GGA.