Open AccessExtensive hypertrophic lupus erythematosus: Atypical presentation
Author(s) -
Tarun Narang,
Meghna Sharma,
N Gulati,
Amrita Kaur
Publication year - 2012
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.103085
Subject(s) - medicine , dermatology , isotretinoin , hydroxychloroquine , lupus erythematosus , systemic lupus erythematosus , disease , pathology , acne , immunology , covid-19 , infectious disease (medical specialty) , antibody
Lupus erythematosus (LE) is a disease with a wide spectrum of cutaneous and systemic manifestations. Clinical features of patients with LE show a great variation, and for this reason it is difficult to develop a unifying concept of this disease. Our objective is to present a case of hypertrophic LE with atypical morphology and extensive involvement, who responded favorably to isotretinoin. Diagnosis of hypertrophic lupus erythematosus (HLE) was confirmed by characteristic histopathological findings. Combination therapy with isotretinoin and hydroxychloroquine resulted in flattening and repression of previously refractory skin lesions. Sometimes, HLE lesions may present a diagnostic and therapeutic dilemma. In long standing lesions, squamous cell carcinoma may arise. Therefore, HLE requires adequate therapy with clinical and histopathological follow up