Open AccessAtypical fibroxanthoma: An unusual skin neoplasm in xeroderma pigmentosum
Author(s) -
Ranjana Bandyopadhyay,
Dipanwita Nag,
Sanjay Bandyopadhyay,
Sankar Narayan Sinha
Publication year - 2012
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/0019-5154.100493
Subject(s) - atypical fibroxanthoma , xeroderma pigmentosum , medicine , dermatology , basal cell , pathology , basal cell carcinoma , neoplasm , melanoma , photodermatosis , dna , cancer research , dna damage , biology , immunohistochemistry , genetics
Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder related to defective deoxyribonucleic acid (DNA) repair. Various cutaneous manifestations related to ultraviolet (UV) damage characterize the clinical course. Primary malignant cutaneous neoplasms like squamous cell carcinoma, basal cell carcinoma and malignant melanoma have been reported. Atypical fibroxanthoma is a rare dermal neoplasm occurring in UV-damaged skin. We report an unusual case of atypical fibroxanthoma in a 20-year-old male with XP.