Open AccessAnaesthetic significance and management of a child with neonatal purpura fulminans
Author(s) -
Akhilesh Kumar Tiwari,
Gaurav Singh Tomar,
Swapnil Tayal,
Madhur Chadha,
Mukul Chandra Kapoor
Publication year - 2012
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.98778
Subject(s) - medicine , purpura fulminans , disseminated intravascular coagulation , intensive care medicine , purpura (gastropod) , coagulopathy , pediatrics , anesthesia , surgery , ecology , biology
Protein C deficiency is a rare autosomal-dominant disorder of varying severity. Patients with homozygous and compound heterozygous protein C deficiency present with neonatal purpura fulminans (NPF). Other presentations usually include disseminated intravascular coagulation and venous thromboembolism. This disorder usually poses a unique anaesthetic challenge to the anaesthesiologist, requiring special precautions to prevent various intra- and post-operative complications. We hereby report the successful anaesthetic management of a 1-month-old infant who presented with NPF.