Open AccessA comparison of high-dose and low-dose tranexamic acid antifibrinolytic protocols for primary coronary artery bypass surgery
Author(s) -
Stephen M. McHugh,
Lavinia Kolarczyk,
Robert Scott Lang,
Lawrence M. Wei,
Marquez Jose,
Kathirvel Subramaniam
Publication year - 2016
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.176279
Subject(s) - medicine , tranexamic acid , perioperative , anesthesia , cardiopulmonary bypass , surgery , coronary artery bypass surgery , artery , aprotinin , antifibrinolytic , blood transfusion , blood loss
Tranexamic acid (TA) is used for prophylactic antifibrinolysis in coronary artery bypass surgeries to reduce bleeding. We evaluated the efficacy of two different doses of TA for prophylactic antifibrinolysis in patients undergoing primary coronary artery bypass grafting (CABG) surgery in this retrospective cohort study at a tertiary care referral centre.