Open AccessBlood transfusion practices in sepsis
Author(s) -
Tvsp Murthy
Publication year - 2014
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.144676
Subject(s) - medicine , sepsis , septic shock , resuscitation , shock (circulatory) , intensive care medicine , blood transfusion , blood product , antibiotics , inotrope , surviving sepsis campaign , oxygen delivery , severe sepsis , anesthesia , immunology , surgery , oxygen , microbiology and biotechnology , biology , chemistry , organic chemistry
Sepsis is a clinical syndrome characterised by systemic inflammation due to infection. There is a spectrum with severity ranging from sepsis to severe sepsis and septic shock. Even with optimal treatment, mortality due to severe sepsis or septic shock is significant and poses a challenge to management. Antibiotics, source control, resuscitation with fluids, vasopressor and inotropic agents are the main-stay of treatment for septic shock. These may be supplemented with transfusion of red blood cells and or blood products, in the case of anaemia to sustain sufficient oxygen delivery([1]) or to manage associated haematological issues. Transfusion in sepsis has always been a debatable issue, especially in relation to choice of the fluid and the role of blood or blood product transfusion.