Open AccessAddition of sub-anaesthetic dose of ketamine reduces gag reflex during propofol based sedation for upper gastrointestinal endoscopy: A prospective randomised double-blind study
Author(s) -
Manish Tandon,
Vijay Pandey,
Razia Bano,
Chandra Kant Pandey,
Nitya Wadhwa
Publication year - 2014
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.138981
Subject(s) - medicine , propofol , anesthesia , sedation , ketamine , confidence interval , placebo , hazard ratio , reflex , incidence (geometry) , prospective cohort study , surgery , alternative medicine , pathology , physics , optics
Gag reflex is unwanted during upper gastrointestinal endoscopy (UGIE). Experimental studies have demonstrated that N-methyl-D-aspartate receptor antagonism prevents gag reflex. We conducted a study to determine if sub-anaesthetic doses of ketamine, added to propofol, reduce the incidence of gag reflex.