Open AccessPerioperative considerations in a sickle cell patient undergoing cardiopulmonary bypass
Author(s) -
Monish S Raut,
Jasbir Singh Khanuja,
Siddharth Srivastava
Publication year - 2014
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.135047
Subject(s) - medicine , cardiopulmonary bypass , perioperative , hypothermia , exchange transfusion , anesthesia , sickle cell anemia , blood transfusion , disease , surgery , pediatrics
An 11-year-old child, a known case of sickle cell anaemia with a history suggestive of sickling crisis in the past was scheduled for surgical pulmonary valvotomy. Pre-operative blood transfusion and hydroxyurea were administered. Pre-operative blood transfusion is indicated in sickle cell disease patients to raise the haematocrit level and lower sickle haemoglobin (HbS) levels. Before the start of cardiopulmonary bypass (CPB), exchange transfusion was performed to reduce HbS level and raise adult haemoglobin level. Hypothermia was prevented by employing normothermic CPB.