Open AccessKounis syndrome resulting from anaphylaxis to diclofenac
Author(s) -
Akhilesh Kumar Tiwari,
Gaurav Singh Tomar,
Col S Ganguly,
Mukul Chandra Kapoor
Publication year - 2013
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.115614
Subject(s) - kounis syndrome , medicine , anaphylaxis , myocardial infarction , cardiology , diclofenac sodium , anesthesia , anaphylactic reaction , acute coronary syndrome , complication , hypersensitivity reaction , allergic reaction , allergy , pharmacology , immunology
"Kounis syndrome" refers to acute coronary syndromes of varying degree (myocardial ischaemia to infarction) induced by mast cell activation as a result of allergic and anaphylactic reactions. ST-segment elevated myocardial infarction is a rare complication that can occur even in patients with normal coronary arteries due to anaphylactic reactions. We present a case that developed acute myocardial infarction following a diclofenac sodium-induced anaphylaxis. The patient did not have any previous coronary artery disease, but there was a temporal relationship with development of the anaphylactic reaction due to diclofenac sodium and the cardiac event. The patient was managed conservatively and the recovery was uneventful.