Open AccessSuurstoftoksisiteit
Author(s) -
C. A. Van der Westhuizen,
M. Viljoen,
M. J. Pitout,
P. H. Van Papendorp
Publication year - 1990
Publication title -
suid-afrikaanse tydskrif vir natuurwetenskap en tegnologie/die suid-afrikaanse tydskrif vir natuurwetenskap en tegnologie
Language(s) - English
Resource type - Journals
eISSN - 2222-4173
pISSN - 0254-3486
DOI - 10.4102/satnt.v9i3.462
Subject(s) - hydrogen peroxide , endoplasmic reticulum , superoxide , oxygen , chemistry , singlet oxygen , hydroxyl radical , reactive oxygen species , mitochondrion , biochemistry , membrane , radical , organic chemistry , enzyme
Oxygen has been discovered about 200 years ago. Since then the vital physiological involvement of oxygen in various biological processes, mainly energy production, has been established. However, in the body molecular oxygen can be converted to toxic oxygen metabolites such as superoxide anion, hydrogen peroxide, the hydroxyl radical and singlet oxygen. These toxic metabolites are produced mainly in the mitochondria, plasma membranes and endoplasmic reticulum