
Signaling pathways involved in the induction of cell death in breast cell lines by a novel carbonic anhydrase 9 inhibitor or antimitotic compound
Author(s) -
Barend André Stander,
Fourie Joubert,
Annie M. Joubert
Publication year - 2012
Publication title -
suid-afrikaanse tydskrif vir natuurwetenskap en tegnologie/die suid-afrikaanse tydskrif vir natuurwetenskap en tegnologie
Language(s) - German
Resource type - Journals
eISSN - 2222-4173
pISSN - 0254-3486
DOI - 10.4102/satnt.v31i1.342
Subject(s) - programmed cell death , microbiology and biotechnology , cell , signal transduction , carbonic anhydrase , antimitotic agent , biology , chemistry , pharmacology , cancer research , biochemistry , apoptosis , enzyme , microtubule , tubulin
Die sintese van ‘n nuut
in silico
-ontwerpte antimitotiese verbinding, C19, wat spesifiek ontwerp
is om selektief te bind aan die kanker geassosieerde koolsuuranhidrase IX (CAIX) proteïen is
uitgevoer deur Ithemba Farmaseutiese maatskappy.