Hypermetabolism of basal ganglia in chorea associated with antiphospholipid antibodies demonstrated by F-18 FDG | Zendy

Mike Sathekge | Zendy; Alex Maes | Zendy; V. Thijst | Zendy; M. De Roo | Zendy

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Hypermetabolism of basal ganglia in chorea associated with antiphospholipid antibodies demonstrated by F-18 FDG

Author(s) -

Mike Sathekge,

Alex Maes,

V. Thijst,

M. De Roo

Publication year - 1997

Publication title -

south african journal of radiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.18

H-Index - 3

eISSN - 2078-6778

pISSN - 1027-202X

DOI - 10.4102/sajr.v2i4.1630

Subject(s) - chorea , medicine , basal ganglia , pathology , antiphospholipid syndrome , hypermetabolism , antibody , radiology , central nervous system , immunology , disease

A brain FDG PET study was performed on a 21-year-old woman with subacute chorea of unknown origin. Associated with her chorea, she had abnormal levels of antiphospholipid antibodies. She had none of the classical features of SLE nor primary antiphospholipid syndrome. The images showed high F-18 FDG uptake in the basal ganglia, while the brain MRI and EEG were normal. An association between chorea and antiphospholipid antibodies had been demonstrated before, with normal brain CT, MRI, 123IMPSPECT and cerebral angiography. The report suggests the advantage of FDG PET in imaging of unexplained cases of chorea associated with antiphospholipid antibodies.

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