Open AccessSystolic function evaluated with cardiovascular magnetic resonance imaging in HIV-infected patients
Author(s) -
Leonie Scholtz,
André Du Plessis,
Savvas Andronikou,
Anelia Swart,
Anton Stoltz,
Aneesah Khan,
Aqeela Moosa
Publication year - 2016
Publication title -
sa journal of radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.18
H-Index - 3
eISSN - 2078-6778
pISSN - 1027-202X
DOI - 10.4102/sajr.v20i2.1044
Subject(s) - medicine , asymptomatic , magnetic resonance imaging , cardiology , cardiac magnetic resonance imaging , human immunodeficiency virus (hiv) , radiology , immunology
Background: Of all areas worldwide, sub-Saharan Africa is worst affected by the HIV and/or AIDS epidemic. Cardiovascular manifestations are very common and are a powerful contributor to mortality, but often go undetected. Cardiovascular magnetic resonance (CMR) is the most reliable method of assessing cardiac function and morphology and, with this in mind, we initiated a cross-sectional study comparing CMR-determined morphological and functional parameters in asymptomatic HIV-infected patients who were not yet on treatment and early in the disease, with HIV-uninfected control patients.Objectives: To ascertain whether there were any morphological abnormalities or systolic functional impairments on CMR in untreated asymptomatic HIV-infected patients, compared with HIV-uninfected control individuals.Methods: The CMR studies were performed using a 1.5-T whole-body clinical magnetic resonance 16-channel scanner (Achieva, Philips Medical Systems, Best, The Netherlands), using a cardiac five-element phased-array receiver coil (SENSE coil). Functional assessment was performed on 36 HIV-infected patients and the findings compared with 35 HIV-uninfected control patients who were matched for age and sex.Results: There was no significant difference in systolic function between the HIV-uninfected and the HIV-infected patients. The left ventricular end diastolic mass (LVEDM) was slightly higher in the HIV-infected group, but this was statistically insignificant.Conclusion: No significant differences were found regarding the CMR systolic functional analysis and morphological parameters between the HIV-infected and the healthy volunteers.